/* Layout: study-protocol pages. Ruled sections on pale bench paper, a 96-well plate as the one signature graphic,
   and one dark viridian band that carries every call to action. */
:root{
  --paper:#F3F5F2; --surface:#FFFFFF; --ink:#13211D; --muted:#55635E; --rule:#D3DBD6;
  --accent:#1C5C4E; --accent-ink:#FFFFFF; --accent-hover:#154A3E; --tint:#E6EDE9; --brass:#8A6714;
  --hit:#B9D3CA; --grid-line:rgba(28,92,78,.07); --head-bg:rgba(243,245,242,.92);
  --band-bg:#17463C; --band-ink:#EEF4F1; --band-muted:#B8CEC5; --band-rule:rgba(238,244,241,.2);
  --field-bg:#FFFFFF; --field-border:#7D8A84; --ok:#1C5C4E; --bad:#A33A2C;
  --shadow:0 1px 0 rgba(19,33,29,.04), 0 18px 40px -22px rgba(19,33,29,.32);
  --font-display:"Newsreader","Iowan Old Style",Georgia,serif;
  --font-body:"Public Sans","Segoe UI",system-ui,-apple-system,sans-serif;
  --font-mono:"IBM Plex Mono",ui-monospace,"SFMono-Regular",Menlo,monospace;
  --fs-xs:.75rem; --fs-sm:.92rem; --fs-base:1.0625rem; --fs-lg:1.2rem; --fs-xl:1.55rem;
  --fs-2xl:clamp(1.9rem,3.6vw,2.6rem); --fs-hero:clamp(2.4rem,5.6vw,4.1rem);
  --radius:10px;
}
@media (prefers-color-scheme: dark){
  :root:not([data-theme="light"]){
    --paper:#0D1412; --surface:#141E1B; --ink:#E2EAE6; --muted:#9BAAA4; --rule:#26342F;
    --accent:#7FC9B5; --accent-ink:#0B1311; --accent-hover:#9DD8C8; --tint:#13241F; --brass:#D9B65C;
    --hit:#2C5248; --grid-line:rgba(127,201,181,.06); --head-bg:rgba(13,20,18,.9);
    --band-bg:#10302A; --band-ink:#E2EEE9; --band-muted:#9FBDB2; --band-rule:rgba(226,238,233,.18);
    --field-bg:#0F1816; --field-border:#66766F; --ok:#7FC9B5; --bad:#F08A7A;
    --shadow:0 1px 0 rgba(0,0,0,.3), 0 18px 40px -22px rgba(0,0,0,.75);
    color-scheme:dark;
  }
}
:root[data-theme="dark"]{
  --paper:#0D1412; --surface:#141E1B; --ink:#E2EAE6; --muted:#9BAAA4; --rule:#26342F;
  --accent:#7FC9B5; --accent-ink:#0B1311; --accent-hover:#9DD8C8; --tint:#13241F; --brass:#D9B65C;
  --hit:#2C5248; --grid-line:rgba(127,201,181,.06); --head-bg:rgba(13,20,18,.9);
  --band-bg:#10302A; --band-ink:#E2EEE9; --band-muted:#9FBDB2; --band-rule:rgba(226,238,233,.18);
  --field-bg:#0F1816; --field-border:#66766F; --ok:#7FC9B5; --bad:#F08A7A;
  --shadow:0 1px 0 rgba(0,0,0,.3), 0 18px 40px -22px rgba(0,0,0,.75);
  color-scheme:dark;
}

/* Base */
*,*::before,*::after{box-sizing:border-box}
html{scroll-behavior:smooth;-webkit-text-size-adjust:100%;scroll-padding-top:96px}
body{margin:0;background:var(--paper);color:var(--ink);font-family:var(--font-body);font-size:var(--fs-base);line-height:1.6;-webkit-font-smoothing:antialiased}
body::before{content:"";position:fixed;inset:0 0 auto;height:env(safe-area-inset-top,0px);z-index:30;background:var(--head-bg)}
img,svg{max-width:100%}
[hidden]{display:none!important}
a{color:var(--accent);text-underline-offset:.18em}
:focus-visible{outline:2px solid var(--accent);outline-offset:3px;border-radius:3px}
h1,h2,h3,h4{font-family:var(--font-display);font-weight:500;line-height:1.1;margin:0;text-wrap:balance;letter-spacing:-.01em}
p,ul,ol,dl,figure{margin:0}
.wrap{max-width:1160px;margin-inline:auto;padding-left:max(24px,env(safe-area-inset-left,0px));padding-right:max(24px,env(safe-area-inset-right,0px))}
.mono{font-family:var(--font-mono);font-size:var(--fs-xs);letter-spacing:.06em;text-transform:uppercase;line-height:1.5}
.eyebrow{font-family:var(--font-mono);font-size:var(--fs-xs);letter-spacing:.09em;text-transform:uppercase;color:var(--accent);font-weight:500;line-height:1.5}
.muted{color:var(--muted)}
.skip{position:absolute;left:-9999px;top:0}
.skip:focus{left:16px;top:16px;z-index:50;background:var(--surface);padding:8px 12px;border-radius:6px}
.visually-hidden{position:absolute!important;width:1px;height:1px;overflow:hidden;clip:rect(0 0 0 0);white-space:nowrap}

/* Buttons and links */
.btn{display:inline-flex;align-items:center;justify-content:center;gap:.5em;font:600 var(--fs-sm)/1 var(--font-body);padding:.95em 1.35em;border-radius:6px;background:var(--accent);color:var(--accent-ink);text-decoration:none;border:1px solid var(--accent);cursor:pointer;transition:background-color .15s,border-color .15s,color .15s}
.btn:hover{background:var(--accent-hover);border-color:var(--accent-hover)}
.btn-ghost{background:transparent;color:var(--ink);border-color:var(--rule)}
.btn-ghost:hover{background:var(--tint);border-color:var(--accent)}
.btn-small{padding:.7em 1.05em}
.cta-row{display:flex;flex-wrap:wrap;gap:12px;align-items:center}
.arrow-link{font-weight:600;text-decoration:none;display:inline-flex;gap:.4em;align-items:center}
.arrow-link::after{content:"\2192";transition:transform .15s}
.arrow-link:hover::after{transform:translateX(3px)}

/* Header */
.site-head{position:sticky;top:env(safe-area-inset-top,0px);z-index:20;background:var(--head-bg);-webkit-backdrop-filter:saturate(1.2) blur(10px);backdrop-filter:saturate(1.2) blur(10px);border-bottom:1px solid var(--rule)}
.head-row{display:flex;align-items:center;justify-content:space-between;gap:20px;padding-block:12px}
.brand{display:inline-flex;align-items:center;gap:11px;color:var(--ink);text-decoration:none;min-width:0}
.mark{width:34px;height:34px;flex:none;color:var(--ink)}
.mark .well{fill:none;stroke:currentColor;stroke-width:1.7}
.mark .lead{fill:var(--accent);stroke:var(--accent);stroke-width:1.5}
.brand-text{display:flex;flex-direction:column;line-height:1}
.brand-name{font-family:var(--font-display);font-size:1.22rem;font-weight:500;letter-spacing:-.01em;white-space:nowrap}
.brand-sub{font-family:var(--font-mono);font-size:.62rem;letter-spacing:.32em;text-transform:uppercase;color:var(--muted);margin-top:5px}
.nav{display:flex;align-items:center;gap:24px}
.nav a{color:var(--ink);text-decoration:none;font-size:var(--fs-sm);font-weight:500}
.nav a:not(.btn):hover,.nav a[aria-current="page"]{color:var(--accent)}
.nav a[aria-current="page"]{text-decoration:underline;text-decoration-thickness:2px;text-underline-offset:.5em}
.nav .btn{color:var(--accent-ink)}
.menu{display:none;position:relative}
.menu summary{list-style:none;cursor:pointer;font:600 var(--fs-sm)/1 var(--font-body);padding:.7em 1em;border:1px solid var(--rule);border-radius:6px;color:var(--ink)}
.menu summary::-webkit-details-marker{display:none}
.menu[open] summary{background:var(--tint)}
.menu-panel{position:absolute;right:0;top:calc(100% + 10px);width:min(280px,calc(100vw - 40px));background:var(--surface);border:1px solid var(--rule);border-radius:var(--radius);box-shadow:var(--shadow);padding:8px;display:flex;flex-direction:column}
.menu-panel a{padding:12px 14px;border-radius:6px;color:var(--ink);text-decoration:none;font-weight:500}
.menu-panel a:hover,.menu-panel a[aria-current="page"]{background:var(--tint);color:var(--accent)}
.menu-panel .btn{margin-top:6px;color:var(--accent-ink)}
.menu-panel .btn:hover{color:var(--accent-ink)}

/* Hero */
.hero{border-bottom:1px solid var(--rule);background-color:var(--paper);background-image:linear-gradient(var(--grid-line) 1px,transparent 1px),linear-gradient(90deg,var(--grid-line) 1px,transparent 1px);background-size:24px 24px;background-position:-1px -1px}
.hero-grid{display:grid;grid-template-columns:minmax(0,1.1fr) minmax(0,.9fr);gap:clamp(36px,5vw,72px);align-items:center;padding-block:clamp(52px,8vw,100px)}
.hero-copy{display:flex;flex-direction:column;gap:24px;min-width:0}
.hero h1{font-size:var(--fs-hero);font-weight:400;letter-spacing:-.025em;line-height:1.03}
.hero h1 em{font-style:italic;color:var(--accent)}
.lede{font-size:var(--fs-lg);color:var(--muted);max-width:34em;line-height:1.55}
.lede strong{color:var(--ink);font-weight:600}
.hero-simple .hero-grid{grid-template-columns:minmax(0,1fr);padding-block:clamp(48px,7vw,84px)}
.hero-simple .hero-copy{max-width:46rem}
.facts-band{border-bottom:1px solid var(--rule)}
.facts{list-style:none;padding:0;display:grid;grid-template-columns:repeat(4,minmax(0,1fr))}
.facts li{display:flex;flex-direction:column;gap:4px;padding:22px 24px 22px 0;min-width:0}
.facts li+li{padding-left:24px;border-left:1px solid var(--rule)}
.fact-k{font-family:var(--font-display);font-size:1.3rem;line-height:1.15}
.fact-v{font-size:var(--fs-sm);color:var(--muted);line-height:1.4}

/* 96-well plate */
.plate{background:var(--surface);border:1px solid var(--rule);border-radius:22px;box-shadow:var(--shadow);padding:clamp(14px,2.2vw,22px);display:flex;flex-direction:column;gap:14px;min-width:0}
.plate-head{display:flex;justify-content:space-between;gap:12px;color:var(--muted)}
.plate-grid{display:grid;grid-template-columns:1.1em repeat(12,minmax(0,1fr));gap:clamp(3px,.6vw,6px);align-items:center}
.plate-grid .lbl{font-family:var(--font-mono);font-size:clamp(.5rem,1vw,.62rem);color:var(--muted);text-align:center;line-height:1}
.well-c{aspect-ratio:1;border-radius:50%;border:1.5px solid var(--rule);background:transparent;max-width:100%}
.well-c.hit{background:var(--hit);border-color:var(--hit)}
.well-c.lead{background:var(--accent);border-color:var(--accent);box-shadow:0 0 0 4px color-mix(in srgb,var(--accent) 22%,transparent)}
.plate figcaption{display:flex;flex-direction:column;gap:4px;padding-top:12px;border-top:1px solid var(--rule)}
.plate figcaption strong{font-family:var(--font-display);font-weight:500;font-size:1.15rem}
.plate figcaption span{font-size:var(--fs-sm);color:var(--muted);line-height:1.5}
.legend{display:flex;flex-wrap:wrap;gap:6px 16px}
.legend span{display:inline-flex;align-items:center;gap:6px}
.legend i{width:9px;height:9px;border-radius:50%;display:inline-block;border:1.5px solid var(--rule)}
.legend i.hit{background:var(--hit);border-color:var(--hit)}
.legend i.lead{background:var(--accent);border-color:var(--accent)}
@media (prefers-reduced-motion: no-preference){
  .well-c.lead{animation:pulse 3.2s ease-in-out infinite}
  @keyframes pulse{50%{box-shadow:0 0 0 7px color-mix(in srgb,var(--accent) 12%,transparent)}}
}

/* Cards that read as documents */
.doc-card{background:var(--surface);border:1px solid var(--rule);border-radius:var(--radius);box-shadow:var(--shadow);overflow:hidden;min-width:0}
.doc-head{display:flex;justify-content:space-between;align-items:center;gap:12px;padding:12px 20px;border-bottom:1px solid var(--rule);background:var(--tint)}
.doc-head .mono{color:var(--muted)}
.doc-head .tag{color:var(--brass);font-weight:500}
.doc-title{padding:20px 20px 4px;font-family:var(--font-display);font-size:1.35rem;line-height:1.2}
.spec{padding:6px 20px 10px;display:grid;grid-template-columns:auto minmax(0,1fr);column-gap:20px;align-items:baseline}
.spec dt,.spec dd{padding-block:11px;border-top:1px solid var(--rule)}
.spec dt{font-family:var(--font-mono);font-size:var(--fs-xs);text-transform:uppercase;letter-spacing:.06em;color:var(--muted);white-space:nowrap}
.spec dd{margin:0;font-size:var(--fs-sm);line-height:1.45}
.spec dt:first-of-type,.spec dd:first-of-type{border-top:0}
.doc-foot{display:flex;justify-content:space-between;align-items:center;gap:12px;flex-wrap:wrap;padding:14px 20px;border-top:1px solid var(--rule)}
.chip{display:inline-flex;align-items:center;gap:8px;padding:6px 11px;border-radius:999px;background:var(--tint);color:var(--accent);font-family:var(--font-mono);font-size:var(--fs-xs);letter-spacing:.04em;font-weight:500;line-height:1.3;white-space:nowrap}
.chip .dot{width:7px;height:7px;border-radius:50%;background:var(--accent);box-shadow:0 0 0 3px color-mix(in srgb,var(--accent) 22%,transparent)}
.chip-brass{background:transparent;color:var(--brass);border:1px solid currentColor}
.checks{list-style:none;padding:6px 20px 14px;display:flex;flex-direction:column}
.checks li{display:grid;grid-template-columns:16px minmax(0,1fr);gap:12px;padding-block:10px;border-top:1px solid var(--rule);font-size:var(--fs-sm);line-height:1.45}
.checks li:first-child{border-top:0}
.checks li::before{content:"";width:14px;height:14px;margin-top:3px;border:1.5px solid var(--muted);border-radius:3px}
.checks li.done::before{background:var(--accent);border-color:var(--accent)}

/* Sections */
.section{padding-block:clamp(64px,9vw,108px);border-bottom:1px solid var(--rule)}
.band-tint{background:var(--tint)}
.stack{display:flex;flex-direction:column;gap:clamp(36px,5vw,56px)}
.section-head{display:flex;flex-direction:column;gap:14px;max-width:46rem}
.section-head h2{font-size:var(--fs-2xl)}
.section-lede{color:var(--muted);font-size:var(--fs-lg);line-height:1.55}
.split{display:grid;grid-template-columns:minmax(0,.9fr) minmax(0,1.1fr);gap:clamp(36px,5vw,72px);align-items:start}
.split-even{grid-template-columns:repeat(2,minmax(0,1fr))}
.split>*{min-width:0}

/* Router cards */
.router{display:grid;grid-template-columns:minmax(0,1.12fr) minmax(0,.88fr);gap:clamp(18px,2.5vw,28px)}
.route{display:flex;flex-direction:column;gap:16px;padding:clamp(24px,3vw,36px);border:1px solid var(--rule);border-radius:var(--radius);background:var(--surface);min-width:0;text-decoration:none;color:var(--ink);transition:border-color .15s,transform .15s}
.route:hover{border-color:var(--accent)}
.route.primary{background:var(--band-bg);border-color:var(--band-bg);color:var(--band-ink)}
.route.primary .mono{color:var(--band-muted)}
.route.primary p{color:var(--band-muted)}
.route.primary .arrow-link{color:var(--band-ink)}
.route .mono{color:var(--accent);font-weight:500}
.route h3{font-size:var(--fs-xl)}
.route p{color:var(--muted)}
.route ul{list-style:none;padding:0;display:flex;flex-wrap:wrap;gap:8px}
.route li{font-size:var(--fs-sm);padding:5px 11px;border:1px solid var(--rule);border-radius:999px}
.route.primary li{border-color:var(--band-rule)}
.route .arrow-link{margin-top:auto;color:var(--accent)}

/* Deal path (where CRO deals stall) */
.dealpath{list-style:none;padding:0;display:grid;grid-template-columns:repeat(5,minmax(0,1fr));counter-reset:none}
.dp{position:relative;display:flex;flex-direction:column;gap:10px;padding:30px 20px 0 0;border-top:2px solid var(--rule);min-width:0}
.dp::before{content:"";position:absolute;top:-8px;left:0;width:14px;height:14px;border-radius:50%;background:var(--tint);border:2px solid var(--accent)}
.dp .mono{color:var(--muted)}
.dp h3{font-size:1.35rem}
.dp .leak{display:flex;flex-direction:column;gap:4px;font-size:var(--fs-sm);line-height:1.5;padding-top:12px;border-top:1px dashed var(--rule)}
.dp .leak .mono{color:var(--bad);font-weight:500}
.dp.is-key{border-top-color:var(--accent)}
.dp.is-key::before{background:var(--accent)}
.dp .chip{align-self:flex-start}
.dealpath-end{display:flex;align-items:center;gap:10px;font-family:var(--font-mono);font-size:var(--fs-xs);letter-spacing:.06em;text-transform:uppercase;color:var(--accent);font-weight:500}

/* Experience list */
.study-groups{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:clamp(20px,3vw,36px)}
.study-group{display:flex;flex-direction:column;gap:10px;min-width:0}
.study-group .mono{color:var(--accent);font-weight:500;padding-bottom:6px;border-bottom:2px solid var(--ink)}
.study-group ul{list-style:none;padding:0}
.study-group li{padding-block:10px;border-bottom:1px solid var(--rule);font-size:var(--fs-sm)}

/* Article teasers */
.posts{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:clamp(18px,2.5vw,28px)}
.post{display:flex;flex-direction:column;gap:12px;padding:clamp(22px,3vw,30px);border:1px solid var(--rule);border-radius:var(--radius);background:var(--surface);text-decoration:none;color:var(--ink);min-width:0;transition:border-color .15s}
.post:hover{border-color:var(--accent)}
.post .meta{display:flex;flex-wrap:wrap;gap:8px 14px;align-items:center;color:var(--muted)}
.post h3{font-size:1.45rem;line-height:1.2}
.post p{color:var(--muted);font-size:var(--fs-sm);line-height:1.55}
.post .arrow-link{margin-top:auto;color:var(--accent)}

/* Comparison table */
.table-wrap{overflow-x:auto;border:1px solid var(--rule);border-radius:var(--radius);background:var(--surface)}
.compare{width:100%;border-collapse:collapse;min-width:640px;font-size:var(--fs-sm)}
.compare th,.compare td{padding:14px 18px;text-align:left;border-bottom:1px solid var(--rule);vertical-align:top}
.compare thead th{font-family:var(--font-mono);font-size:var(--fs-xs);letter-spacing:.06em;text-transform:uppercase;color:var(--muted);font-weight:500;background:var(--tint)}
.compare tbody th{font-weight:600}
.compare tr:last-child th,.compare tr:last-child td{border-bottom:0}
.compare .us{background:color-mix(in srgb,var(--accent) 8%,transparent)}
.compare thead .us{color:var(--accent);background:color-mix(in srgb,var(--accent) 14%,var(--tint))}
.yes{color:var(--ok);font-weight:600}
.no{color:var(--muted)}
.table-note{font-size:var(--fs-sm);color:var(--muted)}

/* Workstreams */
.streams{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:0 clamp(28px,4vw,56px)}
.stream{display:flex;flex-direction:column;gap:10px;padding-block:24px;border-top:1px solid var(--rule);min-width:0}
.stream h3{font-size:var(--fs-xl)}
.stream p{color:var(--muted)}
.stream .gets{display:flex;flex-direction:column;gap:2px;font-size:var(--fs-sm);padding:12px 14px;background:var(--tint);border-radius:8px;color:var(--ink)}
.stream .gets .mono{color:var(--accent);font-weight:500}
.band-tint .stream .gets{background:var(--surface)}

/* Phased timeline */
.phases{list-style:none;padding:0;display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:clamp(18px,2.5vw,28px)}
.phase{display:flex;flex-direction:column;gap:12px;padding:24px;border:1px solid var(--rule);border-radius:var(--radius);background:var(--surface);min-width:0}
.phase .mono{color:var(--accent);font-weight:500}
.phase h3{font-size:1.4rem}
.phase ul{padding-left:1.1em;display:flex;flex-direction:column;gap:6px;font-size:var(--fs-sm);color:var(--muted)}
.after-note{font-size:var(--fs-sm);color:var(--muted);max-width:46rem;padding-left:14px;border-left:2px solid var(--brass)}

/* Fit lists */
.fit{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:clamp(24px,4vw,48px)}
.fit>div{display:flex;flex-direction:column;gap:12px;min-width:0}
.fit h3{font-size:1.35rem;padding-bottom:10px;border-bottom:2px solid var(--ink)}
.fit ul{list-style:none;padding:0}
.fit li{display:grid;grid-template-columns:22px minmax(0,1fr);gap:8px;padding-block:11px;border-bottom:1px solid var(--rule);font-size:var(--fs-sm)}
.fit .good li::before{content:"\2713";color:var(--ok);font-weight:700}
.fit .bad li::before{content:"\2715";color:var(--muted);font-weight:700}

/* Problems trio */
.trio{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:clamp(20px,3vw,36px)}
.trio>div{display:flex;flex-direction:column;gap:10px;padding-top:20px;border-top:2px solid var(--ink);min-width:0}
.trio h3{font-size:1.35rem}
.trio p{color:var(--muted);font-size:var(--fs-sm);line-height:1.6}

/* Annotated quote */
.quote-doc .qrow{display:grid;grid-template-columns:minmax(0,.8fr) minmax(0,1.2fr);gap:20px;padding:14px 20px;border-top:1px solid var(--rule)}
.quote-doc .qrow:first-of-type{border-top:0}
.qline{display:flex;flex-direction:column;gap:2px}
.qline strong{font-weight:600;font-size:var(--fs-sm)}
.qline .mono{color:var(--muted)}
.qnote{font-size:var(--fs-sm);color:var(--ink);line-height:1.5;padding-left:14px;border-left:2px solid var(--brass)}
.qrow.missing{background:color-mix(in srgb,var(--brass) 8%,transparent)}

/* IND track */
.track{list-style:none;padding:0;display:grid;grid-template-columns:repeat(4,minmax(0,1fr))}
.stage{position:relative;padding:30px 24px 0 0;display:flex;flex-direction:column;gap:10px;min-width:0;border-top:2px solid var(--rule)}
.stage::before{content:"";position:absolute;top:-8px;left:0;width:14px;height:14px;border-radius:50%;background:var(--tint);border:2px solid var(--accent)}
.stage .mono{color:var(--muted)}
.stage h3{font-size:1.35rem}
.stage-work{font-size:var(--fs-sm);color:var(--muted);line-height:1.5}
.stage-help{display:flex;flex-direction:column;gap:4px;font-size:var(--fs-sm);line-height:1.5;padding-top:12px;border-top:1px dashed var(--rule)}
.stage-help .mono{color:var(--accent);font-weight:500}
.stage.is-key{border-top-color:var(--accent)}
.stage.is-key::before{background:var(--accent)}
.stage .chip{align-self:flex-start}
.section:not(.band-tint) .stage::before,.section:not(.band-tint) .dp::before{background:var(--paper)}
.section:not(.band-tint) .stage.is-key::before,.section:not(.band-tint) .dp.is-key::before{background:var(--accent)}

/* Disclosure */
.disclosure{display:grid;grid-template-columns:auto minmax(0,1fr);gap:18px;align-items:start;padding:22px 24px;border:1px solid var(--rule);border-left:3px solid var(--brass);border-radius:0 var(--radius) var(--radius) 0;background:var(--surface)}
.disclosure .mono{color:var(--brass);font-weight:500;padding-top:3px}
.disclosure p{font-size:var(--fs-sm);line-height:1.6}

/* FAQ */
.faq{display:flex;flex-direction:column;border-top:1px solid var(--rule);max-width:52rem}
.faq details{border-bottom:1px solid var(--rule)}
.faq summary{cursor:pointer;list-style:none;display:flex;justify-content:space-between;gap:20px;padding-block:20px;font-family:var(--font-display);font-size:1.25rem;line-height:1.3}
.faq summary::-webkit-details-marker{display:none}
.faq summary::after{content:"+";font-family:var(--font-mono);color:var(--accent);font-size:1.2rem;line-height:1.1;transition:transform .15s}
.faq details[open] summary::after{transform:rotate(45deg)}
.faq details p{padding-bottom:20px;color:var(--muted);max-width:44rem}

/* Forms */
.form-card{display:flex;flex-direction:column;gap:18px;padding:clamp(22px,3vw,32px);border:1px solid var(--rule);border-radius:var(--radius);background:var(--surface);box-shadow:var(--shadow);min-width:0}
.form-card h2,.form-card h3{font-size:1.5rem}
.form-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:16px}
.field{display:flex;flex-direction:column;gap:6px;min-width:0}
.field.full{grid-column:1/-1}
.field label,.field .label{font-size:var(--fs-sm);font-weight:600}
.field .hint{font-weight:400;color:var(--muted)}
.field input,.field select,.field textarea{font:inherit;font-size:1rem;color:var(--ink);background:var(--field-bg);border:1px solid var(--field-border);border-radius:6px;padding:.75em .85em;width:100%;min-width:0}
.field textarea{min-height:130px;resize:vertical}
.field input:focus,.field select:focus,.field textarea:focus{outline:2px solid var(--accent);outline-offset:1px;border-color:var(--accent)}
.check{display:grid;grid-template-columns:20px minmax(0,1fr);gap:10px;align-items:start;font-size:var(--fs-sm)}
.check input{width:18px;height:18px;margin:2px 0 0;accent-color:var(--accent)}
.fine{font-size:.82rem;color:var(--muted);line-height:1.5}
.form-status{font-size:var(--fs-sm);color:var(--accent);min-height:1.4em}
.hp{position:absolute;left:-9999px}

/* About */
.portrait{aspect-ratio:4/5;border-radius:var(--radius);border:1px solid var(--rule);background:var(--surface);overflow:hidden;position:relative;max-width:100%}
.portrait img{width:100%;height:100%;object-fit:cover;display:block}
.portrait-placeholder{position:absolute;inset:0;display:flex;flex-direction:column;justify-content:space-between;padding:22px;background-image:radial-gradient(circle,var(--rule) 1.6px,transparent 1.8px);background-size:22px 22px;background-position:11px 11px}
.portrait-placeholder .initials{font-family:var(--font-display);font-style:italic;font-size:4.5rem;line-height:1;color:var(--accent);background:var(--surface);align-self:flex-start;padding:4px 10px;border-radius:8px}
.portrait-placeholder .mono{color:var(--muted);background:var(--surface);align-self:flex-start;padding:4px 8px;border-radius:4px}
.prose{display:flex;flex-direction:column;gap:18px;max-width:40rem}
.pillars{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:0 clamp(24px,4vw,48px)}
.pillar{display:flex;flex-direction:column;gap:6px;padding-block:20px;border-top:1px solid var(--rule);min-width:0}
.pillar h3{font-size:1.3rem}
.pillar p{color:var(--muted);font-size:var(--fs-sm)}
.roles{display:flex;flex-direction:column}
.roles .mono{color:var(--muted);padding-bottom:10px}
.roles dl{margin:0}
.role{display:grid;grid-template-columns:minmax(0,1fr) auto;gap:4px 20px;padding-block:14px;border-top:1px solid var(--rule)}
.role:last-child{border-bottom:1px solid var(--rule)}
.role dt{font-weight:600}
.role dd{margin:0}
.role .role-what{grid-column:1;color:var(--muted);font-size:var(--fs-sm)}
.role .role-since{grid-column:2;grid-row:1;font-family:var(--font-mono);font-size:var(--fs-xs);letter-spacing:.06em;text-transform:uppercase;color:var(--muted);align-self:center}

/* Article */
.article-head{display:flex;flex-direction:column;gap:18px;max-width:46rem}
.article-head h1{font-size:clamp(2.1rem,4.6vw,3.3rem);font-weight:400;letter-spacing:-.02em;line-height:1.08}
.byline{display:flex;flex-wrap:wrap;gap:8px 16px;align-items:center;color:var(--muted)}
.article-body{max-width:42rem;margin-inline:auto;display:flex;flex-direction:column;gap:1.15em;font-size:1.125rem;line-height:1.7}
.article-body h2{font-size:1.65rem;margin-top:1.1em}
.article-body ul,.article-body ol{padding-left:1.3em;display:flex;flex-direction:column;gap:.4em}
.article-body strong{font-weight:600}
.article-body .callout{padding:20px 22px;border-radius:var(--radius);background:var(--tint);display:flex;flex-direction:column;gap:12px;align-items:flex-start;font-size:1rem}
.article-body .callout p{line-height:1.6}
.back-link{font-size:var(--fs-sm)}

/* Contact band */
.cta-band{background:var(--band-bg);color:var(--band-ink);border-bottom:0}
.cta-grid{display:grid;grid-template-columns:minmax(0,1.1fr) minmax(0,.9fr);gap:clamp(36px,5vw,72px);align-items:center}
.cta-copy{display:flex;flex-direction:column;gap:18px;min-width:0}
.cta-band .eyebrow{color:var(--band-muted)}
.cta-band h2{font-size:var(--fs-2xl)}
.cta-copy p{color:var(--band-muted);font-size:var(--fs-lg);line-height:1.55;max-width:32em}
.cta-card{display:flex;flex-direction:column;gap:16px;padding:26px;border:1px solid var(--band-rule);border-radius:12px;min-width:0}
.cta-card .mono{color:var(--band-muted)}
.cta-band .btn{background:var(--band-ink);color:var(--band-bg);border-color:var(--band-ink)}
.cta-band .btn:hover{background:transparent;color:var(--band-ink)}
.cta-band .btn-ghost{background:transparent;color:var(--band-ink);border-color:var(--band-rule)}
.cta-band .btn-ghost:hover{border-color:var(--band-ink)}
.email{font-family:var(--font-display);font-size:clamp(1.15rem,2.4vw,1.5rem);overflow-wrap:anywhere;-webkit-user-select:all;user-select:all}
.copy-status{font-size:var(--fs-sm);min-height:1.4em}
.cta-band .copy-status{color:var(--band-muted)}
.info-list{display:flex;flex-direction:column;gap:18px}
.info-list>div{display:flex;flex-direction:column;gap:4px}
.info-list .mono{color:var(--muted)}
.next-steps{list-style:none;padding:0;display:flex;flex-direction:column;counter-reset:step}
.next-steps li{counter-increment:step;display:grid;grid-template-columns:32px minmax(0,1fr);gap:10px;padding-block:10px;border-top:1px solid var(--rule);font-size:var(--fs-sm)}
.next-steps li::before{content:counter(step);font-family:var(--font-display);font-style:italic;font-size:1.3rem;line-height:1.1;color:var(--accent)}

/* Footer */
.site-foot{background:var(--band-bg);color:var(--band-muted);border-top:1px solid var(--band-rule);font-size:var(--fs-sm)}
.foot-grid{display:grid;grid-template-columns:minmax(0,1.4fr) repeat(3,minmax(0,1fr));gap:32px;padding-block:48px 28px}
.foot-grid>div{display:flex;flex-direction:column;gap:10px;min-width:0}
.site-foot .brand{color:var(--band-ink)}
.site-foot .mark{color:var(--band-ink)}
.site-foot .mark .lead{fill:var(--band-ink);stroke:var(--band-ink)}
.site-foot .brand-sub{color:var(--band-muted)}
.site-foot .mono{color:var(--band-ink);opacity:.7}
.site-foot a{color:var(--band-ink);text-decoration:none}
.site-foot a:hover{text-decoration:underline}
.foot-base{display:flex;flex-wrap:wrap;justify-content:space-between;gap:10px 24px;padding-block:20px 28px;border-top:1px solid var(--band-rule)}

/* Responsive */
@media (max-width:1020px){
  .nav{display:none}
  .menu{display:block}
  .dealpath{grid-template-columns:repeat(3,minmax(0,1fr));row-gap:40px}
  .track{grid-template-columns:repeat(2,minmax(0,1fr));row-gap:40px}
  .facts{grid-template-columns:repeat(2,minmax(0,1fr))}
  .facts li:nth-child(3){padding-left:0;border-left:0}
  .facts li:nth-child(n+3){border-top:1px solid var(--rule)}
}
@media (max-width:900px){
  .hero-grid,.split,.cta-grid,.router{grid-template-columns:minmax(0,1fr)}
  .phases,.trio{grid-template-columns:minmax(0,1fr)}
  .foot-grid{grid-template-columns:repeat(2,minmax(0,1fr))}
  .foot-grid>div:first-child{grid-column:1/-1}
}
@media (max-width:720px){
  .streams,.fit,.posts,.study-groups,.pillars,.split-even{grid-template-columns:minmax(0,1fr)}
  .dealpath{grid-template-columns:minmax(0,1fr);row-gap:30px}
  .dp{border-top:0;border-left:2px solid var(--rule);padding:0 0 0 26px}
  .dp::before{top:2px;left:-8px}
  .dp.is-key{border-left-color:var(--accent)}
  .quote-doc .qrow{grid-template-columns:minmax(0,1fr);gap:8px}
  .form-grid{grid-template-columns:minmax(0,1fr)}
}
@media (max-width:560px){
  .wrap{padding-left:max(20px,env(safe-area-inset-left,0px));padding-right:max(20px,env(safe-area-inset-right,0px))}
  .brand-name{font-size:1.08rem}
  .mark{width:30px;height:30px}
  .facts{grid-template-columns:minmax(0,1fr)}
  .facts li,.facts li+li{padding:16px 0;border-left:0}
  .facts li+li{border-top:1px solid var(--rule)}
  .track{grid-template-columns:minmax(0,1fr);row-gap:30px}
  .stage{border-top:0;border-left:2px solid var(--rule);padding:0 0 0 26px}
  .stage::before{top:2px;left:-8px}
  .stage.is-key{border-left-color:var(--accent)}
  .spec{grid-template-columns:minmax(0,1fr)}
  .spec dt{padding-bottom:0}
  .spec dd{border-top:0;padding-top:2px}
  .disclosure{grid-template-columns:minmax(0,1fr);gap:8px}
  .foot-grid{grid-template-columns:minmax(0,1fr)}
}
@media (prefers-reduced-motion: reduce){
  html{scroll-behavior:auto}
  *{transition:none!important;animation:none!important}
}

/* ---- Biotech partnering additions ---- */
/* Three-way router on the home page */
.router-3{grid-template-columns:minmax(0,1.1fr) repeat(2,minmax(0,.95fr))}
@media (max-width:1020px){.router-3{grid-template-columns:minmax(0,1fr)}}

/* Three-up post grid */
.posts-3{grid-template-columns:repeat(3,minmax(0,1fr))}
@media (max-width:1020px){.posts-3{grid-template-columns:repeat(2,minmax(0,1fr))}}
@media (max-width:720px){.posts-3{grid-template-columns:minmax(0,1fr)}}

/* Cross-link bar between biotech pages */
.crosslink-band{padding-block:28px;border-bottom:1px solid var(--rule)}
.crosslink{display:flex;flex-wrap:wrap;align-items:center;justify-content:space-between;gap:12px 28px;padding:18px 22px;border:1px solid var(--rule);border-left:3px solid var(--accent);border-radius:0 var(--radius) var(--radius) 0;background:var(--surface)}
.crosslink p{font-size:var(--fs-sm);line-height:1.55;max-width:46rem}
.crosslink strong{font-weight:600}

/* Method steps: outputs read as positive, not as leaks */
.dp .stage-work{min-height:0}
.dp .leak.out .mono{color:var(--accent)}

/* Partner-readiness scorecard */
.scorecard{display:grid;grid-template-columns:minmax(0,1.2fr) minmax(0,.8fr);gap:clamp(24px,4vw,48px);align-items:start}
.score-list{margin:0;min-width:0;display:flex;flex-direction:column;padding:6px 22px;border:1px solid var(--rule);border-radius:var(--radius);background:var(--surface);box-shadow:var(--shadow)}
.score-list label{display:grid;grid-template-columns:22px minmax(0,1fr);gap:12px;padding-block:14px;border-top:1px solid var(--rule);font-size:var(--fs-sm);line-height:1.5;cursor:pointer}
.score-list label:first-of-type{border-top:0}
.score-list input{width:18px;height:18px;margin:2px 0 0;accent-color:var(--accent);cursor:pointer}
.score-list label:has(input:checked) span{color:var(--muted)}
.score-result{position:sticky;top:96px;display:flex;flex-direction:column;gap:14px;padding:clamp(22px,3vw,30px);border-radius:var(--radius);background:var(--band-bg);color:var(--band-ink);min-width:0}
.score-result .mono{color:var(--band-muted)}
.score-num{font-family:var(--font-display);font-size:clamp(3rem,6vw,4.2rem);line-height:1}
.score-num small{font-size:.38em;color:var(--band-muted)}
.score-meter{height:8px;border-radius:999px;background:var(--band-rule);overflow:hidden}
.score-meter i{display:block;height:100%;width:0;background:var(--band-ink);transition:width .25s ease}
.score-band{font-family:var(--font-display);font-size:1.45rem;line-height:1.2}
.score-advice{color:var(--band-muted);font-size:var(--fs-sm);line-height:1.55}
.score-gaps{display:flex;flex-direction:column;gap:6px;padding-top:12px;border-top:1px solid var(--band-rule)}
.score-gaps ul{padding-left:1.1em;display:flex;flex-direction:column;gap:4px;font-size:var(--fs-sm)}
.score-result .btn{background:var(--band-ink);color:var(--band-bg);border-color:var(--band-ink)}
.score-result .btn:hover{background:transparent;color:var(--band-ink)}
@media (max-width:900px){.scorecard{grid-template-columns:minmax(0,1fr)}.score-result{position:static}}

/* Contact prefill note */
.prefill-note{font-size:var(--fs-sm);padding:10px 12px;border-radius:6px;background:var(--tint);color:var(--ink)}